High pretransplant HBV level predicts HBV reactivation after kidney transplantation in HBV infected recipients

High pretransplant HBV level predicts HBV reactivation after kidney transplantation in HBV infected recipients

PURPOSE HBsAg-positive kidney recipients are at increased risk for mortality and graft failure. The aims of this study were to identify the outcomes of HBsAg-positive recipients who received preemptive antiviral agents after successful kidney transplantation and to analyze risk factors for HBV reactivation. METHODS We retrospectively reviewed the medical records of 944 patients performed kidn...

Outcomes and risk factors for hepatitis B virus (HBV) reactivation after kidney transplantation in occult HBV carriers.

PURPOSE The purpose of this study was to explore the outcomes and risk factors for hepatitis B virus (HBV) reactivation after kidney transplantation in occult HBV carriers, who are hepatitis B surface antigen (HBsAg) seronegative and hepatitis B core antibody (HBcAb) seropositive before kidney transplantation. METHODS We retrospectively analyzed 322 occult HBV carriers who received kidney tra...

The Relationship between HBSAG and HBV DNA in HBV-Infected Blood Donors

Factors associated with postoperative HBV reactivation in HBV related hepatocellular carcinoma patients with HBV-DNA levels less than the minimum

Objective: This study was aim to clarify the postoperative hepatitis B virus reactivation (PHR) and risk factors of PHR in hepatocellular carcinoma (HCC) patients with hepatitis B virus (HBV)-DNA levels less than the minimum. And to figure out the significance of antiviral therapy on liver function recovery after hepatectomy. Methods: A total of 74 HCC patients with preoperative HBV-DNA levels ...

Doxorubicin activates hepatitis B virus (HBV) replication in HBV-harboring hepatoblastoma cells. A possible novel mechanism of HBV reactivation in HBV carriers receiving systemic chemotherapy.

BACKGROUND Reactivation of HBV replication is a clinically significant complication in HBV(+) patients receiving chemotherapy. We recently found that nearly half of the HBV reactivation in lymphoma patients occurred within 2 weeks of the first dose of chemotherapy. We hypothesized that mechanisms other than immunosuppression, such as direct stimulation of HBV replication by anticancer drugs, mi...